Some of the most popular neighborhoods in Santa Cruz include: Centro Histórico is celebrated for its rich cultural heritage, charming cobblestone streets, and vibrant local markets, making it a hub for history enthusiasts and those seeking a lively atmosphere. São João do Estoril offers a serene coastal lifestyle with beautiful beaches, excellent dining options, and a family-friendly environment, perfect for those who appreciate a relaxed yet active lifestyle. Monte Estoril is known for its elegant architecture, lush gardens, and proximity to cultural landmarks, attracting residents who value sophistication and tranquility. Estoril is famous for its luxurious amenities, including the renowned casino, golf courses, and a vibrant nightlife, appealing to those who enjoy a dynamic and upscale living experience.

The main difference between staying at a hotel and renting one of Blueground’s apartments in Santa Cruz is the comfort and space provided. Unlike a standard hotel room, Blueground’s apartments offer fully furnished homes with kitchens, living rooms, and multiple bedrooms. These apartments in Santa Cruz are designed for extended stays, making them feel more like home than hotel accommodation's temporary feel.